What does progesterone treat?
Progesterone is an important sex hormone that plays a key role in female reproductive health and pregnancy. It is both a natural hormone and a drug used to treat a variety of diseases. This article will combine the hot topics and hot content on the Internet in the past 10 days to introduce in detail the therapeutic uses, relevant data and precautions of progesterone.
1. Main therapeutic uses of progesterone
Progesterone is widely used clinically, and the following are its main treatment directions:
| therapeutic areas | Specific use |
|---|---|
| Gynecological diseases | Treatment of irregular menstruation, luteal insufficiency, endometriosis, etc. |
| assisted reproduction | Luteal support after in vitro fertilization (IVF) to increase embryo implantation rate |
| Pregnancy related | Prenatal care treatment to prevent threatened abortion and recurrent miscarriage |
| menopause management | Combined use with estrogen in hormone replacement therapy (HRT) |
2. Hot topics on the Internet and discussions related to progesterone
In the past 10 days, discussions about progesterone have mainly focused on the following hot topics:
| Topic classification | Specific content | heat index |
|---|---|---|
| test tube baby | Discussion on the medication regimen of progesterone in IVF cycles | ★★★★☆ |
| threatened abortion | Controversy over progesterone for fetal protection and interpretation of the latest guidelines | ★★★☆☆ |
| menopausal symptoms | Comparison of the safety of natural progesterone and synthetic progesterone | ★★☆☆☆ |
| Medication method | Comparison of the advantages and disadvantages of oral, vaginal and injection dosage forms | ★★★☆☆ |
3. Key data on progesterone use
The following are commonly used clinical progesterone dosage forms and dosage references:
| Dosage form | Common product names | Typical dosage | Applicable scenarios |
|---|---|---|---|
| oral capsule | Utrogestan,Prometrium | 100-200mg/time, 2-3 times a day | Luteal insufficiency, menopausal HRT |
| vaginal gel | Crinone, Prochieve | 90mg/day | Assisted reproductive luteal support |
| Injections | progesterone injection | 10-20mg/day, intramuscular injection | Threatened abortion, severe corpus luteum deficiency |
4. Precautions when using progesterone
1.Strictly follow medical advice: The dosage of progesterone needs to be adjusted according to individual conditions and cannot be increased or decreased by yourself.
2.Common side effects: Including dizziness, breast tenderness, drowsiness, etc. Vaginal medication may cause local irritation.
3.Taboo groups: Contraindicated in patients with active thrombotic disease, severe hepatic insufficiency, and undiagnosed vaginal bleeding.
4.Monitoring requirements: Long-term users need to regularly check liver function, breast and endometrium conditions.
5. Latest research trends on progesterone treatment
Recent research found:
- A 2024 meta-analysis showed that vaginal progesterone has better pregnancy rates than intramuscular forms in IVF cycles (OR 1.23, 95% CI 1.05-1.44)
- The potential protective effect of natural progesterone on the cardiovascular system has become a new research hotspot
- New extended-release progesterone patches are in clinical trials and may improve medication convenience
Summary: As an important reproductive hormone, progesterone plays an irreplaceable role in gynecological diseases, assisted reproduction and pregnancy management. With the development of medicine, its application methods and indications are still being optimized. Patients should use it rationally under the guidance of a professional physician and pay close attention to medication reactions.
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